Solubility Enhancement of Domperidone by Solvent Change In situ Micronization Technique
نویسندگان
چکیده
منابع مشابه
Solubility Enhancement of Domperidone Fast Disintegrating Tablet Using Hydroxypropyl-β-Cyclodextrin by Inclusion Complexation Technique
Domperidone Maleate (DOM), an antiemetic drug, has been used in treatment of adults and children. It has low aqueous solubility and hence low bioavailability. In present study, an attempt has been made to enhance the solubility of DOM by inclusion complexation with Hydroxypropyl-βCyclodextrin (HP-β-CD) using kneading technique and formulation of fast disintegrating tablets by using Sodium Starc...
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ژورنال
عنوان ژورنال: Advanced Biomedical Research
سال: 2018
ISSN: 2277-9175
DOI: 10.4103/abr.abr_219_17